The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK1

Breast cancer gene 1 (BRCA1)-associated RING domain protein 1 (BARD1) forms a heterodimer with BRCA1, a tumor suppressor associated with hereditary breast and ovarian cancer. BRCA1/BARD1 functions in multiple cellular processes including DNA repair and centrosome regulation. Centrosomes are the majo...

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Bibliographic Details
Main Authors: Kei Otsuka, Yuki Yoshino, Huicheng Qi, Natsuko Chiba
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/8/842