Establishment of induced pluripotent stem cell (iPSC) line from a 57-year old patient with sporadic Alzheimer's disease

Peripheral blood mononuclear cells (PBMCs) were collected from a clinically characterised 57-year old woman with sporadic Alzheimer's disease. The PMBCs were reprogrammed with the human OSKM transcription factors using the Sendai-virus delivery system. The transgene-free iPSC showed pluripotenc...

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Bibliographic Details
Main Authors: Anna Ochalek, Csilla Nemes, Eszter Varga, Zsuzsanna Táncos, Julianna Kobolák, András Dinnyés
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116300538