Making Visible the Invisible: Automatically Measured Global and Regional Brain Volume Is Associated with Cognitive Impairment and Fatigue in Multiple Sclerosis

In multiple sclerosis (MS), the transition from relapsing-remitting to the secondary-progressive phase is characterized by a progression independent of relapse activity (PIRA), resulting in physical disability accumulation and invisible symptoms, i.e., fatigue and cognitive impairment (CI). These sy...

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Bibliographic Details
Main Authors: Stefano Ziccardi, Francesca Benedetta Pizzini, Maddalena Guandalini, Agnese Tamanti, Cecilia Cristofori, Massimiliano Calabrese
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/1/41