Class C CpG Oligodeoxynucleotide Immunomodulatory Response in Aged Squirrel Monkey (Saimiri Boliviensis Boliviensis)

Class C CpG Oligodeoxynucleotide Immunomodulatory Response in Aged Squirrel Monkey (Saimiri Boliviensis Boliviensis)

One means of stimulating the mammalian innate immune system is via Toll-like receptor 9 (TLR9) being exposed to unmethylated cytosine-phosphate-guanine (CpG) DNA, also known as pathogen-associated molecular patterns (PAMPs) of microbial origin. Synthetic CpG oligodeoxynucleotides (ODNs) with defined...

Full description

Bibliographic Details
Main Authors: Pramod N. Nehete, Lawrence E. Williams, Sriram Chitta, Bharti P. Nehete, Akash G. Patel, Margish D. Ramani, Thomas Wisniewski, Henrieta Scholtzova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
CpG ODN class C
aged squirrel monkey
cerebral amyloid angiopathy
cellular immune response
ELISPOT
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00036/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2020.00036/full

Similar Items