Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol
Abstract Background Over the past decades, survival rates of children born with congenital heart disease (CHD) have increased dramatically. Progress in prenatal diagnosis, less-invasive catheter techniques and perioperative intensive care as well as surgical techniques have led to an increased focus...
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| Format: | Article |
| Language: | English |
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BMC
2019-10-01
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| Series: | Systematic Reviews |
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| Online Access: | http://link.springer.com/article/10.1186/s13643-019-1153-y |
| _version_ | 1819071325973512192 |
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| author | Maria Feldmann Cinzia Ullrich Célina Bataillard Walter Knirsch Martina A. Gosteli-Peter Beatrice Latal Ulrike Held |
| author_facet | Maria Feldmann Cinzia Ullrich Célina Bataillard Walter Knirsch Martina A. Gosteli-Peter Beatrice Latal Ulrike Held |
| author_sort | Maria Feldmann |
| collection | DOAJ |
| description | Abstract Background Over the past decades, survival rates of children born with congenital heart disease (CHD) have increased dramatically. Progress in prenatal diagnosis, less-invasive catheter techniques and perioperative intensive care as well as surgical techniques have led to an increased focus on extracardiac comorbidities, including potential neurodevelopmental sequelae associated with CHD. A growing body of literature reports impairments in early and school-age developmental outcome; however, there is a substantial variability in the spectrum of examined CHD types, assessment ages and applied test batteries. Furthermore, little information is available on executive function impairments in this population. Therefore, the aim of this systematic review is to determine the impact of CHD on intellectual outcome and executive functioning at school age and to determine risk factors for impaired outcomes by means of a systematic search. Methods A systematic review of literature that reports neurodevelopmental outcome in children with CHD undergoing cardiopulmonary bypass surgery. Intelligence quotient or executive function scores will be considered primary outcomes. Databases such as Cochrane, EMBASE, MEDLINE and PsycINFO will be searched. Discussion The results of this systematic review will summarize the current evidence on intellectual and executive function outcome after cardiopulmonary bypass surgery in school-age children with CHD. This review will thus be the basis for better patient and parental counselling and the establishment of tailored follow-up programmes and interventional trials. Systematic review registration In accordance with the guidelines, our systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on January 9, 2019 (CRD42018086568). PROSPERO CRD42019118736. |
| first_indexed | 2024-12-21T17:20:03Z |
| format | Article |
| id | doaj.art-232210fbebab411890538e194ea2314f |
| institution | Directory Open Access Journal |
| issn | 2046-4053 |
| language | English |
| last_indexed | 2024-12-21T17:20:03Z |
| publishDate | 2019-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Systematic Reviews |
| spelling | doaj.art-232210fbebab411890538e194ea2314f2022-12-21T18:56:12ZengBMCSystematic Reviews2046-40532019-10-01811610.1186/s13643-019-1153-yNeurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocolMaria Feldmann0Cinzia Ullrich1Célina Bataillard2Walter Knirsch3Martina A. Gosteli-Peter4Beatrice Latal5Ulrike Held6Child Development Centre, University Children’s Hospital ZurichChild Development Centre, University Children’s Hospital ZurichChild Development Centre, University Children’s Hospital ZurichChildren’s Research Centre, University Children’s Hospital ZurichMain Library, University of ZurichChild Development Centre, University Children’s Hospital ZurichEpidemiology, Biostatistics and Prevention Institute, Department of Biostatistics, University of ZurichAbstract Background Over the past decades, survival rates of children born with congenital heart disease (CHD) have increased dramatically. Progress in prenatal diagnosis, less-invasive catheter techniques and perioperative intensive care as well as surgical techniques have led to an increased focus on extracardiac comorbidities, including potential neurodevelopmental sequelae associated with CHD. A growing body of literature reports impairments in early and school-age developmental outcome; however, there is a substantial variability in the spectrum of examined CHD types, assessment ages and applied test batteries. Furthermore, little information is available on executive function impairments in this population. Therefore, the aim of this systematic review is to determine the impact of CHD on intellectual outcome and executive functioning at school age and to determine risk factors for impaired outcomes by means of a systematic search. Methods A systematic review of literature that reports neurodevelopmental outcome in children with CHD undergoing cardiopulmonary bypass surgery. Intelligence quotient or executive function scores will be considered primary outcomes. Databases such as Cochrane, EMBASE, MEDLINE and PsycINFO will be searched. Discussion The results of this systematic review will summarize the current evidence on intellectual and executive function outcome after cardiopulmonary bypass surgery in school-age children with CHD. This review will thus be the basis for better patient and parental counselling and the establishment of tailored follow-up programmes and interventional trials. Systematic review registration In accordance with the guidelines, our systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on January 9, 2019 (CRD42018086568). PROSPERO CRD42019118736.http://link.springer.com/article/10.1186/s13643-019-1153-yCongenital heart diseaseNeurocognitive outcomeIntellectual outcomeIQExecutive functionSchool-age |
| spellingShingle | Maria Feldmann Cinzia Ullrich Célina Bataillard Walter Knirsch Martina A. Gosteli-Peter Beatrice Latal Ulrike Held Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol Systematic Reviews Congenital heart disease Neurocognitive outcome Intellectual outcome IQ Executive function School-age |
| title | Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol |
| title_full | Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol |
| title_fullStr | Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol |
| title_full_unstemmed | Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol |
| title_short | Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol |
| title_sort | neurocognitive outcome of school aged children with congenital heart disease who underwent cardiopulmonary bypass surgery a systematic review protocol |
| topic | Congenital heart disease Neurocognitive outcome Intellectual outcome IQ Executive function School-age |
| url | http://link.springer.com/article/10.1186/s13643-019-1153-y |
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