Development of <sup>18</sup>F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

Development of <sup>18</sup>F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

Pretargeted PET imaging is an emerging and fast-developing method to monitor immuno-oncology strategies. Currently, tetrazine ligation is considered the most promising bioorthogonal reaction for pretargeting in vivo. Recently, we have developed a method to <sup>18</sup>F-label ultrareact...

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Bibliographic Details
Main Authors: Rocío García-Vázquez, Jesper Tranekjær Jørgensen, Klas Erik Bratteby, Vladimir Shalgunov, Lars Hvass, Matthias M. Herth, Andreas Kjær, Umberto Maria Battisti
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceuticals
Subjects:
bioorthogonal chemistry
tetrazine ligation
bispyridyl tetrazines
pretargeted imaging
PET
fluorine-18
Online Access:https://www.mdpi.com/1424-8247/15/2/245

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https://www.mdpi.com/1424-8247/15/2/245

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