Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder

Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder

Bladder urothelial cell carcinoma (UCC) incidence is about three times higher in men compared with women. There are several indications for the involvement of hormonal factors in the aetiology of UCC. Here, we provide evidence of androgen signalling in UCC progression. Microarray and qPCR analysis r...

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Bibliographic Details
Main Authors: Maria V. Luna‐Velez, Jelmer J. Dijkstra, Marina A. Heuschkel, Frank P. Smit, Guillaume van de Zande, Dominique Smeets, J. P. Michiel Sedelaar, Michiel Vermeulen, Gerald W. Verhaegh, Jack A. Schalken
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Molecular Oncology
Subjects:
androgen deprivation therapy
androgen receptor
cell migration
colony formation
transcriptome analysis
urothelial cell carcinoma
Online Access:https://doi.org/10.1002/1878-0261.12957

Internet

https://doi.org/10.1002/1878-0261.12957

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