Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study

Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study

Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes persistent synovitis, bone damage, and progressive joint destruction. Neuroimmune modulation through electrical stimulation of the vagus nerve activates the inflammatory reflex and has been shown t...

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Bibliographic Details
Main Authors: Daniel Peterson, Mark Van Poppel, Warren Boling, Perry Santos, Jason Schwalb, Howard Eisenberg, Ashesh Mehta, Heather Spader, James Botros, Frank D. Vrionis, Andrew Ko, P. David Adelson, Bradley Lega, Peter Konrad, Guillermo Calle, Fernando L. Vale, Richard Bucholz, R. Mark Richardson
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Bioelectronic Medicine
Subjects:
Vagus nerve stimulation
Rheumatoid arthritis
Inflammatory reflex
Neuroimmune modulation
Online Access:https://doi.org/10.1186/s42234-023-00138-x

Internet

https://doi.org/10.1186/s42234-023-00138-x

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