Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes

Abstract Autoimmune diseases result from autoantigen-mediated activation of adaptive immunity; intriguingly, autoantigen-specific T cells are also present in healthy donors. An assessment of dynamic changes of this autoreactive repertoire in both health and disease is thus warranted. Here we investi...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Anne Eugster, Anna Lorenc, Martin Kotrulev, Yogesh Kamra, Manisha Goel, Katja Steinberg-Bains, Shereen Sabbah, Sevina Dietz, Ezio Bonifacio, Mark Peakman, Iria Gomez-Tourino
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2024-10-01
Ráidu:Nature Communications
Liŋkkat:https://doi.org/10.1038/s41467-024-53255-9