Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons

Summary: The transport and translation of dendritic mRNAs by RNA-binding proteins (RBPs) allows for spatially restricted gene expression in neuronal processes. Although local translation in neuronal dendrites is now well documented, there is little evidence for corresponding effects on local synapti...

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Main Authors: Matthew E. Klein, Thomas J. Younts, Carmen Freire Cobo, Adina R. Buxbaum, Jonathan Aow, Hediye Erdjument-Bromage, Stéphane Richard, Roberto Malinow, Thomas A. Neubert, Robert H. Singer, Pablo E. Castillo, Bryen A. Jordan
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313300