Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications
Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. Hypoxia affects histone modifications by altering the activities of histone-modifying enzymes and the levels of hypoxia-inducible factor (HIF) isoforms. Synthetic hypox...
Main Authors: | Kuo-Feng Hsu, Sarah E. Wilkins, Richard J. Hopkinson, Rok Sekirnik, Emily Flashman, Akane Kawamura, James S.O. McCullagh, Louise J. Walport, Christopher J. Schofield |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-01-01
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Series: | Epigenetics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/15592294.2020.1786305 |
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