Pan-cancer landscape of epigenetic factor expression predicts tumor outcome

Abstract Oncogenic pathways that drive cancer progression reflect both genetic changes and epigenetic regulation. Here we stratified primary tumors from each of 24 TCGA adult cancer types based on the gene expression patterns of epigenetic factors (epifactors). The tumors for five cancer types (ACC,...

Full description

Bibliographic Details
Main Authors: Michael W. Cheng, Mithun Mitra, Hilary A. Coller
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05459-w