Distinct Stress Response and Altered Striatal Transcriptome in Alpha-Synuclein Overexpressing Mice

Parkinson’s disease (PD) is a progressive neurodegenerative disorder with motor symptoms and a plethora of non-motor and neuropsychiatric features that accompany the disease from prodromal to advanced stages. While several genetic defects have been identified in familial forms of PD, the predominanc...

Full description

Bibliographic Details
Main Authors: Zinah Wassouf, Thomas Hentrich, Nicolas Casadei, Mirko Jaumann, Marlies Knipper, Olaf Riess, Julia M. Schulze-Hentrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.01033/full