Involvement of mitochondrial dysfunction in pathogenesis of hemophagocytic lymphohistiocytosis

Involvement of mitochondrial dysfunction in pathogenesis of hemophagocytic lymphohistiocytosis

Background: Hemophagocytic lymphohistiocytosis (HLH) is a hyper-inflammatory condition resulting from altered crosstalk between innate and adaptive immune responses. Familial HLH is caused by mutations in several genes whereas the acquired form is associated with infections, rheumatic diseases, mali...

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Bibliographic Details
Main Authors: Mazhor Aldosary, Maha Al-Otaibi, Fatima Al-Fadhli, Namik Kaya, Raashda Sulaiman, Mohammed Al-Owain
Format: Article
Language:English
Published: Discover STM Publishing Ltd 2019-06-01
Series:Journal of Biochemical and Clinical Genetics
Subjects:
hemophagocytic lymphohistiocytosis
mitochondrial dysfunction
inherited metabolic
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=18963

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http://www.ejmanager.com/fulltextpdf.php?mno=18963

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