Predictors of discontinuation, efficacy, and safety of memantine treatment for Alzheimer’s disease: meta-analysis and meta-regression of 18 randomized clinical trials involving 5004 patients

Predictors of discontinuation, efficacy, and safety of memantine treatment for Alzheimer’s disease: meta-analysis and meta-regression of 18 randomized clinical trials involving 5004 patients

Abstract Background The risk-benefit relationship of memantine treatment for Alzheimer’s disease (AD) remains unclear. In addition, variability between the results of clinical trials has been observed. The aim of this study was to investigate the risk-benefit relationship of memantine treatment in p...

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Bibliographic Details
Main Authors: Lídia Blanco-Silvente, Dolors Capellà, Josep Garre-Olmo, Joan Vilalta-Franch, Xavier Castells
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Geriatrics
Subjects:
Alzheimer’s disease
Memantine
Discontinuation
Efficacy
Meta-analysis
Meta-regression
Online Access:http://link.springer.com/article/10.1186/s12877-018-0857-5

Internet

http://link.springer.com/article/10.1186/s12877-018-0857-5

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