CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Abstract Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride and bicarbonate channel in secretory epithelia with a critical role in maintaining fluid homeostasis. Mutations in CFTR are associated with Cystic Fibrosis (CF), the most common lethal autosomal recessive disorder in C...

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Main Authors: Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Format: Article
Language:English
Published: Springer Nature 2022-02-01
Series:Molecular Systems Biology
Subjects:
cystic fibrosis
high‐throughput screening
integrative computational biology
interactome
mammalian membrane two‐hybrid
Online Access:https://doi.org/10.15252/msb.202110629

Internet

https://doi.org/10.15252/msb.202110629

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