Physiologically based toxicokinetic modelling of Tri(2-chloroethyl) phosphate (TCEP) in mice accounting for multiple exposure routes

Physiologically based toxicokinetic modelling of Tri(2-chloroethyl) phosphate (TCEP) in mice accounting for multiple exposure routes

Exposure routes are important for health risk assessment of chemical risks. The application of physiologically based toxicokinetic (PBTK) models to predict concentrations in vivo can determine the effects of harmful substances and tissue accumulation on the premise of saving experimental costs. In t...

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Bibliographic Details
Main Authors: Jiaqi Ding, Wanyu He, Wanxiao Sha, Guoqiang Shan, Lingyan Zhu, Lin Zhu, Jianfeng Feng
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
TCEP
PBTK model
Mouse
Multiple Exposure Routes
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324000514

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http://www.sciencedirect.com/science/article/pii/S0147651324000514

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