Physiologically based toxicokinetic modelling of Tri(2-chloroethyl) phosphate (TCEP) in mice accounting for multiple exposure routes

Physiologically based toxicokinetic modelling of Tri(2-chloroethyl) phosphate (TCEP) in mice accounting for multiple exposure routes

Exposure routes are important for health risk assessment of chemical risks. The application of physiologically based toxicokinetic (PBTK) models to predict concentrations in vivo can determine the effects of harmful substances and tissue accumulation on the premise of saving experimental costs. In t...

Full description

Bibliographic Details
Main Authors:	Jiaqi Ding, Wanyu He, Wanxiao Sha, Guoqiang Shan, Lingyan Zhu, Lin Zhu, Jianfeng Feng
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	TCEP PBTK model Mouse Multiple Exposure Routes
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651324000514

Similar Items

The Application of a Physiologically Based Toxicokinetic Model in Health Risk Assessment
by: Mengting Chen, et al.
Published: (2023-10-01)

Tris(2-chloroethyl) Phosphate (TCEP) Elicits Hepatotoxicity by Activating Human Cancer Pathway Genes in HepG2 Cells
by: Abdullah M. Al-Salem, et al.
Published: (2020-11-01)

Accurate measurement of sulfhydryls and TCEP-releasable sulfhydryls in the liquid phase of wine that contribute to ‘reductive’ aromas using LC-MS/MS
by: Marlize Z. Bekker, et al.
Published: (2024-04-01)

iTCep: a deep learning framework for identification of T cell epitopes by harnessing fusion features
by: Yu Zhang, et al.
Published: (2023-05-01)

Alleviation of Tris(2-chloroethyl) Phosphate Toxicity on the Marine Rotifer <i>Brachionus plicatilis</i> by Polystyrene Microplastics: Features and Molecular Evidence
by: Wenqian Ma, et al.
Published: (2022-04-01)

Effects of tris(2-chloroethyl) phosphate exposure on chicken embryos in a shell-less incubation system
by: Kazuki Kanda, et al.
Published: (2021-01-01)

High Efficiency RNA Extraction From Sperm Cells Using Guanidinium Thiocyanate Supplemented With Tris(2-Carboxyethyl)Phosphine
by: Martin Roszkowski, et al.
Published: (2021-04-01)

Urinary metabolites of organophosphate flame retardants in China: Health risk from tris(2-chloroethyl) phosphate (TCEP) exposure
by: Tao Zhang, et al.
Published: (2018-12-01)

Parental whole life-cycle exposure to tris (2-chloroethyl) phosphate (TCEP) disrupts embryonic development and thyroid system in zebrafish offspring
by: Hongkai Wang, et al.
Published: (2022-12-01)

High performance liquid chromatographic analysis of reduction products of a thiolated DNA for immobilization on gold nanoparticles
by: Fatemeh Javadi-Zarnaghi, et al.
Published: (2019-07-01)

Extending Regulatory Biokinetic Lead Models towards Food Safety: Evaluation of Consumer Baby Food Contribution to Infant Blood Lead Levels and Variability
by: Skyler A. Price, et al.
Published: (2023-07-01)

Reducing agents facilitate membrane patch seal integrity and longevity
by: Damayantee Das, et al.
Published: (2024-12-01)

Determination of disulfide bridges of two spider toxins: hainantoxin-III and hainantoxin-IV
by: W Wang, et al.
Published: (2009-01-01)

Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models
by: Colin G. Scanes, et al.
Published: (2022-04-01)

Semivolatile compounds in schools and their influence on cognitive performance of children
by: Hans-Peter Hutter, et al.
Published: (2013-08-01)

CHANGES OF DEHYDROASCORBIC ACID CONTENT IN RELATION TO TOTAL CONTENT OF VITAMIN C IN SELECTED FRUITS AND VEGETABLES
by: Artur Mazurek, et al.
Published: (2012-12-01)

Toxicokinetics and toxicity of nanoparticles in the course of inhalation exposure
by: Berta Fal, et al.
Published: (2020-09-01)

Disruption of Membrane Integrity as a Molecular Initiating Event Determines the Toxicity of Polyhexamethylene Guanidine Phosphate Depending on the Routes of Exposure
by: Jeongah Song, et al.
Published: (2022-03-01)

Identification of a putative methyltransferase gene of Babesia bigemina as a novel molecular biomarker uniquely expressed in parasite tick stages
by: Gamila A. R. Bohaliga, et al.
Published: (2018-08-01)

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure
by: Zannatul Ferdous, et al.
Published: (2020-03-01)

Biodistribution Survey of Oxidized Single-Wall Carbon Nanohorns Following Different Administration Routes by Using Label-Free Multispectral Optoacoustic Tomography
by: Shi Y, et al.
Published: (2019-12-01)

THE INFLUENCE OF SEXUAL VIOLENCE CODE EXPOSURE TOWARD PARENTS’ COGNITION ROUTES
by: Rahmiati D., et al.
Published: (2017-11-01)

Route of Arsenic Exposure Differentially Impacts the Expression of Genes Involved in Gut-Mucosa-Associated Immune Responses and Gastrointestinal Permeability
by: Kuppan Gokulan, et al.
Published: (2023-03-01)

Toxicokinetics of β-Amanitin in Mice and In Vitro Drug–Drug Interaction Potential
by: Young Yoon Bang, et al.
Published: (2022-04-01)

Ecological risk assessment for tris(2-chloroethyl) phosphate to freshwater organisms
by: Yu Qiao, et al.
Published: (2022-09-01)

Consumption of Rodenticide Baits by Invertebrates as a Potential Route into the Diet of Insectivores
by: Emily J. Williams, et al.
Published: (2023-12-01)

Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, Volume II
by: Yanzhu Zhu, et al.
Published: (2023-01-01)

NNIR: N-Non-Intersecting-Routing Algorithm for Multi-Path Resilient Routing in Telecommunications Applications
by: Lewis Veryard, et al.
Published: (2020-03-01)

Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans
by: Tarana Arman, et al.
Published: (2021-07-01)

Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S
by: Jeremy Gingrich, et al.
Published: (2021-02-01)

Study on BGP route leak
by: Jia JIA,Jian JIN, et al.
Published: (2016-08-01)

Maritime route and vessel tracklet dataset for vessel-to-route association
by: Clément Iphar, et al.
Published: (2022-10-01)

Adaptive Elitist Genetic Algorithm With Improved Neighbor Routing Initialization for Electric Vehicle Routing Problems
by: Yanfei Zhu, et al.
Published: (2021-01-01)

Comparison of toxicokinetic properties of eleven analogues of Bisphenol A in pig after intravenous and oral administrations
by: Clémence A. Gély, et al.
Published: (2023-01-01)

The transhumance route of Pithoragarh: A cultural route?
by: Samiksha Srichandan, et al.
Published: (2021-12-01)

Human biomonitoring and toxicokinetics as key building blocks for next generation risk assessment
by: Elena Reale, et al.
Published: (2024-02-01)

Research on Routes of Shiraz to Isfahan
by: mohammadali jodaki, et al.
Published: (2016-03-01)

Health Risk Assessment for Artificial Turf Playgrounds in School Athletic Facilities: Multi-route Exposure Estimation for Use Patterns
by: Ho-Hyun Kim, et al.
Published: (2012-09-01)

Implicit flood routing in natural channels /
by: 432098 Amein, Michael

Performance Evaluation of Routing Metrics in the LOADng Routing Protocol
by: Jose V. V. Sobral, et al.
Published: (2017-06-01)