Synthesis and Evaluation of Thymol-Based Synthetic Derivatives as Dual-Action Inhibitors against Different Strains of <i>H. pylori</i> and AGS Cell Line

Synthesis and Evaluation of Thymol-Based Synthetic Derivatives as Dual-Action Inhibitors against Different Strains of <i>H. pylori</i> and AGS Cell Line

Following a similar approach on carvacrol-based derivatives, we investigated the synthesis and the microbiological screening against eight strains of <i>H. pylori</i>, and the cytotoxic activity against human gastric adenocarcinoma (AGS) cells of a new series of ether compounds based on...

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Bibliographic Details
Main Authors: Francesca Sisto, Simone Carradori, Paolo Guglielmi, Mattia Spano, Daniela Secci, Arianna Granese, Anatoly P. Sobolev, Rossella Grande, Cristina Campestre, Maria Carmela Di Marcantonio, Gabriella Mincione
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
thymol
<i>Helicobacter pylori</i>
AGS cells
semi-synthesis
drug resistance
dual-action agents, antimicrobial activity
Online Access:https://www.mdpi.com/1420-3049/26/7/1829

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https://www.mdpi.com/1420-3049/26/7/1829

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