Efficacy of Disease Modifying Therapies in Progressive MS and How Immune Senescence May Explain Their Failure

Efficacy of Disease Modifying Therapies in Progressive MS and How Immune Senescence May Explain Their Failure

The advent of disease modifying therapies (DMT) in the past two decades has been the cornerstone of successful clinical management of multiple sclerosis (MS). Despite the great strides made in reducing the relapse frequency and occurrence of new signal changes on neuroimaging in patients with relaps...

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Bibliographic Details
Main Authors: Navid Manouchehri, Victor H. Salinas, Negar Rabi Yeganeh, David Pitt, Rehana Z. Hussain, Olaf Stuve
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neurology
Subjects:
adaptive immunity
innate immunity
multiple sclerosis
immunosenescence
progressive multiple sclerosis
disease modifying therapies
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.854390/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.854390/full

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