Complex seizure disorder caused by Brunol4 deficiency in mice.
Idiopathic epilepsy is a common human disorder with a strong genetic component, usually exhibiting complex inheritance. We describe a new mouse mutation in C57BL/6J mice, called frequent-flyer (Ff), in which disruption of the gene encoding RNA-binding protein Bruno-like 4 (Brunol4) leads to limbic a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-07-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1934399?pdf=render |