Synaptic modulation of glutamate in striatum of the YAC128 mouse model of Huntington disease

Synaptic modulation of glutamate in striatum of the YAC128 mouse model of Huntington disease

Background: Altered balance between striatal direct and indirect pathways contributes to early motor, cognitive and psychiatric symptoms in Huntington disease (HD). While degeneration of striatal D2-type dopamine receptor (D2)-expressing indirect pathway medium spiny neurons (iMSNs) occurs prior to...

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Bibliografische gegevens
Hoofdauteurs: Judy Cheng, Ellen T. Koch, Daniel Ramandi, James P. Mackay, Timothy P. O’Leary, William Rees-Jones, Lynn A. Raymond
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2025-02-01
Reeks:Neurobiology of Disease
Onderwerpen:
Huntington disease
Striatum
Corticostriatal synapse
Glutamate
Dopamine
Endocannabinoids
Online toegang:http://www.sciencedirect.com/science/article/pii/S0969996124003760

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http://www.sciencedirect.com/science/article/pii/S0969996124003760

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