Towards a unified biological hypothesis for the BDNF Val66Met-associated memory deficits in humans: a model of impaired dendritic mRNA trafficking

Towards a unified biological hypothesis for the BDNF Val66Met-associated memory deficits in humans: a model of impaired dendritic mRNA trafficking

Brain-derived neurotrophic factor (BDNF) represents promotesa key molecule for the survival and differentiation of specific populations of neurons in the central nervous system. BDNF also regulates plasticity-related processes underlying memory and learning. A common single nucleotide polymorphism (...

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Bibliographic Details
Main Authors: Gabriele eBaj, Davide eCarlino, Lucia eGardossi, Enrico eTongiorgi
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Neuroscience
Subjects:
BDNF
Post-traumatic stress disorder
neurotrophins
memory deficits
hippocampus atrophy
dendritic mRNA trafficking
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00188/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00188/full

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