Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility

Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility

A prevalent cause of sperm dysfunction in male infertility patients is the overproduction of reactive oxygen species, an attendant increase in lipid peroxidation and the production of cytotoxic reactive carbonyl species such as 4-hydroxynonenal. Our previous studies have implicated arachidonate 15-l...

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Bibliographic Details
Main Authors: Jessica L. H. Walters, Amanda L. Anderson, Sarah J. Martins da Silva, R. John Aitken, Geoffry N. De Iuliis, Jessie M. Sutherland, Brett Nixon, Elizabeth G. Bromfield
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
male infertility
lipid peroxidation
spermatozoa
lipoxygenase
Online Access:https://www.mdpi.com/2076-3921/10/1/43

Internet

https://www.mdpi.com/2076-3921/10/1/43

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