Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer’s Disease Progression

Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer’s Disease Progression

Compelling evidence supports the role of oxidative stress in Alzheimer’s disease (AD) pathophysiology. Interestingly, Herpes simplex virus-1 (HSV-1), a neurotropic virus that establishes a lifelong latent infection in the trigeminal ganglion followed by periodic reactivations, has been reportedly li...

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Bibliographic Details
Main Authors: Virginia Protto, Antonella Tramutola, Marco Fabiani, Maria Elena Marcocci, Giorgia Napoletani, Federica Iavarone, Federica Vincenzoni, Massimo Castagnola, Marzia Perluigi, Fabio Di Domenico, Giovanna De Chiara, Anna Teresa Palamara
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Microorganisms
Subjects:
Herpes simplex virus-1
HSV-1
oxidative stress
redox proteomics
Alzheimer’s disease
Online Access:https://www.mdpi.com/2076-2607/8/7/972

Internet

https://www.mdpi.com/2076-2607/8/7/972

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