Yap/Taz transcriptional activity is essential for vascular regression via Ctgf expression and actin polymerization.

Vascular regression is essential to remove redundant vessels during the formation of an efficient vascular network that can transport oxygen and nutrient to every corner of the body. However, no mechanism is known to explain how major blood vessels regress during development. Here we use the dorsal...

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Bibliographic Details
Main Authors: Ayumi Nagasawa-Masuda, Kenta Terai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5378338?pdf=render