Novel platform for quantitative evaluation of medicinal efficacy based on contractility of artificial skeletal muscle

Novel platform for quantitative evaluation of medicinal efficacy based on contractility of artificial skeletal muscle

Atrophy is characterized by muscle weakness and reduced mobility and results from inactivity, aging, cancer cachexia, and excessive glucocorticoid use. Skeletal muscle is essential for locomotion and energy production and accounts for a significant portion of body weight. Loss of muscle function adv...

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Bibliographic Details
Main Authors: Kota KISHISHITA, Tomohiro NAKAMURA, Marino MIZUTANI, Toshia FUJISATO, Takeshi HASHIMOTO, Naoko MATSUI, Hiroko MARUKI-UCHIDA, Naoki IEMOTO, Sho YOKOYAMA
Format: Article
Language:English
Published: The Japan Society of Mechanical Engineers 2023-12-01
Series:Journal of Biomechanical Science and Engineering
Subjects:
artificial skeletal muscle
c2c12
contractile force
drug evaluation
muscle contractility
Online Access:https://www.jstage.jst.go.jp/article/jbse/18/4/18_23-00396/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jbse/18/4/18_23-00396/_pdf/-char/en

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