Western Diet-Fed, Aortic-Banded Ossabaw Swine

Summary: The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population. This report provides evidence supporting the hypothesis that Western Diet−fed, aortic-banded Ossabaw swine display an integrated p...

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Main Authors: T. Dylan Olver, PhD, Jenna C. Edwards, BS, Thomas J. Jurrissen, BS, Adam B. Veteto, MS, John L. Jones, MS, Chen Gao, BS, Christoph Rau, PhD, Chad M. Warren, MS, Paula J. Klutho, PhD, Linda Alex, PhD, Stephanie C. Ferreira-Nichols, BS, Jan R. Ivey, BS, Pamela K. Thorne, MS, Kerry S. McDonald, PhD, Maike Krenz, MD, Christopher P. Baines, PhD, R. John Solaro, PhD, Yibin Wang, PhD, David A. Ford, PhD, Timothy L. Domeier, PhD, Jaume Padilla, PhD, R. Scott Rector, PhD, Craig A. Emter, PhD
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19300646