Development of lactate‐related gene signature and prediction of overall survival and chemosensitivity in patients with colorectal cancer

Abstract Background Colorectal cancer (CRC) is a malignant tumor of the digestive system that contains high levels of immune cells. Lactic acid, a major metabolite, plays a crucial role in tumor development, maintenance, and therapeutic response. However, the prognostic potential and therapeutic bio...

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Bibliographic Details
Main Authors: Zhi Tong, Xinyu Wang, Sanbao Shi, Tiewei Hou, Guangrong Gao, Da Li, Yongqi Shan, Cheng Zhang
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.5682