Role of tumor-associated neutrophils in regulation of tumor growth in lung cancer development: A mathematical model.

Neutrophils display rapid and potent innate immune responses in various diseases. Tumor-associated neutrophils (TANs) however either induce or overcome immunosuppressive functions of the tumor microenvironment through complex tumor-stroma crosstalk. We developed a mathematical model to address the q...

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Bibliographic Details
Main Authors: Yangjin Kim, Donggu Lee, Junho Lee, Seongwon Lee, Sean Lawler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211041