The identification of intact HIV proviral DNA from human cerebrospinal fluid

The identification of intact HIV proviral DNA from human cerebrospinal fluid

We evaluated the HIV-1 DNA reservoir in peripheral blood mononuclear cells (PBMC) and cerebrospinal fluid (CSF) in people with HIV (PWH) and associations to cognitive dysfunction. Using the intact proviral DNA assay (IPDA), an emerging technique to identify provirus that may be the source of viral r...

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Autori principali: Zhan Zhang, Monica D. Reece, Sebastian Roa, William Tyor, Donald R. Franklin, Scott L. Letendre, Vincent C. Marconi, Albert M. Anderson, Christina Gavegnano
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2024-07-01
Serie:Neurotherapeutics
Soggetti:
HIV
Reservoir
Central nervous system
Cerebrospinal fluid
Inflammation
Accesso online:http://www.sciencedirect.com/science/article/pii/S187874792400059X

Accesso online

http://www.sciencedirect.com/science/article/pii/S187874792400059X

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