Role of α2-Adrenoceptor Subtypes in Suppression of L-Type Ca<sup>2+</sup> Current in Mouse Cardiac Myocytes

Sarcolemmal α2 adrenoceptors (α2-AR), represented by α2A, α2B and α2C isoforms, can safeguard cardiac muscle under sympathoadrenergic surge by governing Ca<sup>2+</sup> handling and contractility of cardiomyocytes. Cardiomyocyte-specific targeting of α2-AR would provide cardiac muscle-de...

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Bibliographic Details
Main Authors: Edward V. Evdokimovskii, Ryounghoon Jeon, Sungjo Park, Oleg Y. Pimenov, Alexey E. Alekseev
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/8/4135