Autophagy responsive intra-intercellular delivery nanoparticles for effective deep solid tumor penetration

Autophagy responsive intra-intercellular delivery nanoparticles for effective deep solid tumor penetration

Abstract Deep tumor cells (cells in the center of solid tumors) play a crucial role in drug tolerance, metastasis, recurrence and microenvironment immune suppression. However, their deep location endows them with an untouched abdomen and makes them refractory to current treatments. Herein, we exploi...

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Bibliographic Details
Main Authors: Fengling Wang, Dandan Xie, Wenjing Lai, Min Zhou, Jie Wang, Rufu Xu, Jingbing Huang, Rong Zhang, Guobing Li
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Nanobiotechnology
Subjects:
Autophagy responsive
Transcellular transport
Deep penetration
Solid tumors
Online Access:https://doi.org/10.1186/s12951-022-01514-6

Internet

https://doi.org/10.1186/s12951-022-01514-6

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