Gene Expression Comparison between the Lymph Node-Positive and -Negative Reveals a Peculiar Immune Microenvironment Signature and a Theranostic Role for WNT Targeting in Pancreatic Ductal Adenocarcinoma: A Pilot Study

Gene Expression Comparison between the Lymph Node-Positive and -Negative Reveals a Peculiar Immune Microenvironment Signature and a Theranostic Role for WNT Targeting in Pancreatic Ductal Adenocarcinoma: A Pilot Study

Over the past several years there has been much debate with regards to the prognostic and clinical significance of pancreatic ductal adenocarcinoma (PDAC) with lymph nodes metastasis. The PDAC gene expression knowledge and the biologic alterations underlying the lymph node involvement convey a clini...

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Bibliographic Details
Main Authors: Antonella Argentiero, Simona De Summa, Roberta Di Fonte, Rosa Maria Iacobazzi, Letizia Porcelli, Matteo Da Vià, Oronzo Brunetti, Amalia Azzariti, Nicola Silvestris, Antonio Giovanni Solimando
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
pancreatic cancer
PDAC
lymph node metastases
WNT
dendritic cells
M2 macrophages
XAV-939
ANGPTL4
MST-1
tumor immune microenvironment
Online Access:https://www.mdpi.com/2072-6694/11/7/942

Internet

https://www.mdpi.com/2072-6694/11/7/942

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