Characterization of Properties, In Vitro and In Vivo Evaluation of Calcium Phosphate/Amino Acid Cements for Treatment of Osteochondral Defects

Characterization of Properties, In Vitro and In Vivo Evaluation of Calcium Phosphate/Amino Acid Cements for Treatment of Osteochondral Defects

Novel calcium phosphate cements containing a mixture of four amino acids, glycine, proline, hydroxyproline and either lysine or arginine (CAL, CAK) were characterized and used for treatment of artificial osteochondral defects in knee. It was hypothesized that an enhanced concentration of extracellul...

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Bibliographic Details
Main Authors: Lubomir Medvecky, Maria Giretova, Radoslava Stulajterova, Jan Danko, Katarina Vdoviakova, Lenka Kresakova, Zdenek Zert, Eva Petrovova, Katarina Holovska, Maros Varga, Lenka Luptakova, Tibor Sopcak
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Materials
Subjects:
calcium phosphate cement
amino acid
osteochondral defect
hyaline cartilage
pig model
Online Access:https://www.mdpi.com/1996-1944/14/2/436

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https://www.mdpi.com/1996-1944/14/2/436

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