Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6

Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6

Summary: Emerging evidence shows that pancreatic β-cell function and quality are key determinants in the progression of type 2 diabetes (T2D). The transcription factor zinc finger homeobox 2 (Zhx2) is involved in proliferation and development of multiple cells. However, the exact role of Zhx2 in β-c...

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Bibliographic Details
Main Authors: Lu Ding, Yankun Zhang, Yingchun Wang, Yuzhen Wang, Zheng Tong, Pengfei Li, Chaojia Chen, Bo Wang, Xuetian Yue, Chunyang Li, Zhuanchang Wu, Xiaohong Liang, Chunhong Ma, Lifen Gao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Molecular biology
Endocrinology
Model organism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223009483

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http://www.sciencedirect.com/science/article/pii/S2589004223009483

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