PEGDA-based HistoBrick for increasing throughput of cryosectioning and immunohistochemistry in organoid and small tissue studies

PEGDA-based HistoBrick for increasing throughput of cryosectioning and immunohistochemistry in organoid and small tissue studies

Abstract Histology is the gold standard for analyzing tissue structure and cell morphology. Immunostaining on thin tissue sections enables precise visualization of antigens and proteins. However, for cryosectioning small tissues such as organoids, spheroids, and tumoroids there is a lack of standard...

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Bibliographic Details
Main Authors: Emilie Vuille-dit-Bille, Larissa Utz, Fiona E. Müllner, Valeria J. Arteaga-Moreta, Yanyan Hou, Stefan E. Spirig, Diane Ledroit-Paic, Sarah Heub, Jonas Goldowsky, Gilles Weder, Magdalena Renner
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
3D cell models
Microtissues
Organoids
Spheroids
Human retinal organoids
Histology
Online Access:https://doi.org/10.1038/s41598-024-83164-2

Internet

https://doi.org/10.1038/s41598-024-83164-2

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