Alterations in the testicular parenchyma of Foxn1+/- and Foxn1-/- adult mice

Alterations in the testicular parenchyma of Foxn1+/- and Foxn1-/- adult mice

Abstract Nude mice carry an autosomal recessive mutation in the Foxn1 gene and therefore are homozygous recessive animals (Foxn1 -/-). The fertility rate of homozygous male (Foxn1-/-) is low, which seems to be related to the delay in the production of gametes at the beginning of sexual maturity. The...

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Main Authors: FERNANDA C.R. DIAS, SÉRGIO L.P. MATTA, MICHELLE B. SOARES, ELIZABETH L. OLIVEIRA, FABIANA C.S.A. MELO, NIVALDO A. PARIZOTTO, ANGELICA O. GOMES, MARCOS L.M. GOMES
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2022-06-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Spermatogenesis
germ cells
Leydig cells
androgen
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300601&lng=en&tlng=en

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