Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

Background: To evaluate the utility of polygenic risk scores (PRSs) in identifying high-risk individuals, different publicly available PRSs for breast (n=85), prostate (n=37), colorectal (n=22), and lung cancers (n=11) were examined in a prospective study of 21,694 Chinese adults. Methods: We constr...

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Bibliographic Details
Main Authors: Peh Joo Ho, Iain BeeHuat Tan, Dawn Qingqing Chong, Chiea Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Rajkumar Dorajoo, Jingmei Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
population-based cancer screening
polygenic risk score
cohort study
Asian
calibration
Online Access:https://elifesciences.org/articles/82608

Internet

https://elifesciences.org/articles/82608

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