Alcohol Dependence Modulates Amygdalar mTORC2 and PKCε Expression in a Rodent Model

Alcohol Dependence Modulates Amygdalar mTORC2 and PKCε Expression in a Rodent Model

Multiple alcohol use disorder (AUD)-related behavioral alterations are governed by protein kinase C epsilon (PKCε), particularly in the amygdala. Protein kinase C (PKC) is readily phosphorylated at Ser729 before activation by the mTORC2 protein complex. In keeping with this, the current study was co...

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Bibliographic Details
Main Authors: Athirah Hanim, Isa N. Mohamed, Rashidi M. P. Mohamed, Mohd Helmy Mokhtar, Suzana Makpol, Ruth Naomi, Hasnah Bahari, Haziq Kamal, Jaya Kumar
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Nutrients
Subjects:
alcohol
amygdala
mTOR
mTORC2
mTORC1
PKC epsilon
Online Access:https://www.mdpi.com/2072-6643/15/13/3036

Internet

https://www.mdpi.com/2072-6643/15/13/3036

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