Effect of aromatic substituents on thermoresponsive functional polycaprolactone micellar carriers for doxorubicin delivery

Effect of aromatic substituents on thermoresponsive functional polycaprolactone micellar carriers for doxorubicin delivery

Amphiphilic functional polycaprolactone (PCL) diblock copolymers are excellent candidates for micellar drug delivery. The functional groups on the backbone significantly affect the properties of PCL. A systematic investigation of the effect of aromatic substituents on the self-assembly of γ-function...

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Bibliographic Details
Main Authors: Hanghang Wang, Himanshu Polara, Abhi Bhadran, Tejas Shah, Godwin Kweku Babanyinah, Ziyuan Ma, Erika L. Calubaquib, Justin T. Miller, Michael C. Biewer, Mihaela C. Stefan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
functionalized polycaprolactone
amphiphilic diblock copolymers
thermoresponsive polymers
polymeric micelles
drug delivery
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1356639/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1356639/full

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