A standardized framework for risk-based assessment of treatment effect heterogeneity in observational healthcare databases

Abstract Treatment effects are often anticipated to vary across groups of patients with different baseline risk. The Predictive Approaches to Treatment Effect Heterogeneity (PATH) statement focused on baseline risk as a robust predictor of treatment effect and provided guidance on risk-based assessm...

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Bibliographic Details
Main Authors: Alexandros Rekkas, David van Klaveren, Patrick B. Ryan, Ewout W. Steyerberg, David M. Kent, Peter R. Rijnbeek
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-023-00794-y