Histone Lysine Demethylase JMJD2D/KDM4D and Family Members Mediate Effects of Chronic Social Defeat Stress on Mouse Hippocampal Neurogenesis and Mood Disorders

Histone Lysine Demethylase JMJD2D/KDM4D and Family Members Mediate Effects of Chronic Social Defeat Stress on Mouse Hippocampal Neurogenesis and Mood Disorders

Depression, anxiety and related mood disorders are major psychiatric illnesses worldwide, and chronic stress appears to be one of the primary underlying causes. Therapeutics to treat these debilitating disorders without a relapse are limited due to the incomplete molecular understanding of their eti...

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Bibliographic Details
Main Authors: Swati Maitra, Nitin Khandelwal, Scherazad Kootar, Pooja Sant, Salil S. Pathak, Sujatha Reddy, Annapoorna P. K., Upadhyayula Suryanarayana Murty, Sumana Chakravarty, Arvind Kumar
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Brain Sciences
Subjects:
jumonji domain-containing histone demethylases
Dimethyloxallyl glycine (DMOG)
epigenetic regulators
chromatin modifications
dentate gyrus (DG)
neural stem or progenitor cells (NSCs/NPCs)
Online Access:https://www.mdpi.com/2076-3425/10/11/833

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https://www.mdpi.com/2076-3425/10/11/833

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