SPIRAL MRI for in vivo lithium-7 imaging: a feasibility study in mice after oral lithium treatment

Abstract Lithium has been the frontline treatment for bipolar disorder for over 60 years. However, its mode of action and distribution in the brain is still incompletely understood. The primary isotope of lithium, lithium-7 (7Li), is a magnetic resonance (MR) active, spin-3/2 nucleus. However, its l...

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Bibliographic Details
Main Authors: Tor Rasmus Memhave, Amir Moussavi, Susann Boretius
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50841-7