CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers

CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers

Abstract Background Epigenetic modifications established in mammalian gametes are largely reprogrammed during early development, however, are partly inherited by the embryo to support its development. In this study, we examine CpG island (CGI) sequences to predict whether a mouse blastocyst CGI inhe...

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Bibliographic Details
Main Authors: Osamu Maruyama, Yinuo Li, Hiroki Narita, Hidehiro Toh, Wan Kin Au Yeung, Hiroyuki Sasaki
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Bioinformatics
Subjects:
Recurrent neural network
Gated recurrent unit
Classification
Oocyte
Blastocyst
Embryo
Online Access:https://doi.org/10.1186/s12859-022-04916-3

Internet

https://doi.org/10.1186/s12859-022-04916-3

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