CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers
Abstract Background Epigenetic modifications established in mammalian gametes are largely reprogrammed during early development, however, are partly inherited by the embryo to support its development. In this study, we examine CpG island (CGI) sequences to predict whether a mouse blastocyst CGI inhe...
Main Authors: | Osamu Maruyama, Yinuo Li, Hiroki Narita, Hidehiro Toh, Wan Kin Au Yeung, Hiroyuki Sasaki |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-09-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-022-04916-3 |
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