Periodic Variation of Mutation Rates in Bacterial Genomes Associated with Replication Timing

ABSTRACT The causes and consequences of spatiotemporal variation in mutation rates remain to be explored in nearly all organisms. Here we examine relationships between local mutation rates and replication timing in three bacterial species whose genomes have multiple chromosomes: Vibrio fischeri, Vib...

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Bibliographic Details
Main Authors: Marcus M. Dillon, Way Sung, Michael Lynch, Vaughn S. Cooper
Format: Article
Language:English
Published: American Society for Microbiology 2018-09-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01371-18