Development of a tissue augmented Bayesian model for expression quantitative trait loci analysis

Development of a tissue augmented Bayesian model for expression quantitative trait loci analysis

Expression quantitative trait loci (eQTL) analyses detect genetic variants (SNPs) associated with RNA expression levels of genes. The conventional eQTL analysis is to perform individual tests for each gene-SNP pair using simple linear regression and to perform the test on each tissue separately igno...

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Bibliographic Details
Main Authors: Yonghua Zhuang, Kristen Wade, Laura M. Saba, Katerina Kechris
Format: Article
Language:English
Published: AIMS Press 2020-01-01
Series:Mathematical Biosciences and Engineering
Subjects:
eqtl
bayesian model
allele-specific expression
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2020007?viewType=HTML

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https://www.aimspress.com/article/doi/10.3934/mbe.2020007?viewType=HTML

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