Zoom in on Antibody Aggregates: A Potential Pitfall in the Search of Rare EV Populations

High-resolution flow cytometers (hFCM) are used for the detection of extracellular vesicles (EV) in various biological fluids. Due to the increased sensitivity of hFCM, new artifacts with the potential of interfering with data interpretation are introduced, such as detection of antibody aggregates....

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Bibliographic Details
Main Authors: Rikke W. Rasmussen, Jaco Botha, Frederik Prip, Mathilde Sanden, Morten H. Nielsen, Aase Handberg
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/2/206