The evolution of pepsinogen C genes in vertebrates: duplication, loss and functional diversification.

<h4>Background</h4>Aspartic proteases comprise a large group of enzymes involved in peptide proteolysis. This collection includes prominent enzymes globally categorized as pepsins, which are derived from pepsinogen precursors. Pepsins are involved in gastric digestion, a hallmark of vert...

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Bibliographic Details
Main Authors: Luís Filipe Costa Castro, Monica Lopes-Marques, Odete Gonçalves, Jonathan Mark Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032852&type=printable